The most commonly used method for the covalent binding of biomolecules onto 1-D nanostructures is through the diimide-activated amidation of carboxylic acid terminated nanostructures.

最常法是通过端羧酸基纳米结构二酰亚胺活化氨基化合物来进行物子与1-D纳米结构共价结合。