E2 protein, including hypervariable region 1 (HVR1) in the N-terminal region, contains some epitopes that can induce neutralizing antibodies.

括高变区的E2蛋白含有中和性表位，能诱导机体产生中和性体。

After the tolerizing regimen, the host is withdrawn from the suppressive agents, but is able to maintain specific immune tolerance to the immunogenic epitopes present on the toleragen.

在方案后，将免疫抑制剂从宿主撤离，宿主仍能保持对存在于上的免疫性表位的特异性免疫。