CONCLUSION The QSAR model can predict the MIC of carbapenems and select the biologic-activity compounds, which offer a new way of thinking and references of carbapenems compounds design.

结论所建立的QSAR模型能有效地进霉烯类化合物的MIC值的预测和化合物筛选，为类新药开发提供新的参考和思路。