Binucleated granulocyte appeared in the stage from promyelocyte to neutrophilic band form with mostly symmetry mirror image characteristics in size and shape.

双核粒细胞在早幼至杆状核阶段均见存在,多具有大小形状八字形特点。

The main adverse reactions were hematologic toxicity. The manifestations were : WBC, neutrophile granulocyte, blood platelet and hemoglobin all decreased, then was digestive canal symptoms.

主要不良反应为血液学毒性,表现为细胞下降、中性粒细胞下降、血小板下降和血红下降,其次为消化道症状。