Actually, we can use the British slang to express it, that is: hard cheese.

(cheese,虽然“乳酪、奶酪”的意思，于波斯语“chiz 事情、东西”) 表示不顺利、倒霉。

All her attempts to find a better job were unsuccessful; it seemed that the dice were loaded against her.

她想找个好点的工作, 可一的努力都没成功。她总不顺利。