Alternatively, a new version of a gene can also be created through reverse transcription: during gene expression, the mRNA is copied back into a sequence of DNA that is inserted into the genome.

其二，新基因复本也可能透过反录，基因表出来mRNA反录成DNA序列，再插回基因组内，这种象称为反录移（retrotransposition），发生在细胞内称为长散布核因子（LINE）子活动时。